Table 1. Prior case reports of fluoroquinolone-associated vasculitis.

Fluoroquinolone (FQ)	Dose	Time to symptom onset	Other medications	Clinical diagnosis or biopsy proven	Final diagnosis	Treatment	Year Published
Ciprofloxacin17	500 mg po BID	3 days	None	Skin biopsy	Perivascular mononuclear-cell infiltrate	Withdrawal of FQ	1989
Ciprofloxacin18	500 po mg/day	4 days	Cephradine	Skin biopsy	LCV	Withdrawal of FQ	1992
Ciprofloxacin18	Unknown	10 days	Diuretic	Clinical diagnosis	Haemorrhagic vasculitis	None	1992
Ciprofloxacin19	500 mg po BID	4 days	Fluoxetine	Clinical diagnosis	Cutaneous vasculitis	Withdrawal of FQ; fluoxetine continued	1997
Ciprofloxacin20	Unknown	10 days	None	Clinical diagnosis; subsequent renal biopsy	Cutaneous vasculitis	Withdrawal of FQ; prednisone	2007
Ciprofloxacin4	Unknown	7 days	Rifampin	Clinical diagnosis	Drug-induced vasculitis	Withdrawal of FQ; rifampin given without recurrence	2009
Ciprofloxacin4	Unknown	8 days	Flucloxacillin	Clinical diagnosis	Drug hypersensitivity	Withdrawal of FQ; flucloxacillin continued	2009
Ofloxacin21	200 mg po BID	1 day	None	Skin biopsy and mast cell degranulation test for ofloxacin	Leukocytoclastic angiitis	Withdrawal of FQ; prednisone	1989
Ofloxacin22	200 mg po BID	5 days	Bumetanide, spirinolactone 2 weeks prior	Skin biopsy	Vasculitis	Unknown	1989
Ofloxacin23	200 mg po BID	3 days	Aspirin, digoxin	Skin biopsy	Leukocytoclastic vasculitis	Withdrawal of FQ; prednisolone	1995
Ofloxacin24	200 mg po BID	3 days	None	Skin biopsy	Leukocytoclastic angiitis	Withdrawal of FQ	1996
Levofloxacin25	500 mg po daily	3 days	None	Clinical diagnosis	Nephrotoxicity and purpura	Withdrawal of FQ; prednisone	2002
Levofloxacin26	500 mg po daily	5 days	Azithromycine, piperacilline- tazobactam	Clinical diagnosis	LCV	Withdrawal of FQ; prednisone	2006
Levofloxacin4	Unknown	3 days	Rifampin	Skin biopsy	LCV	Withdrawal of FQ and rifampin changed to rifampicin	2009
Levofloxacin	500 mg po BID	5 days	None	Skin biopsy	LCV	Withdrawal of FQ; prednisone	Current case