Changes in diarrheal status before (Day 0) and during 6 days of treatment after induction of colitis (TNBS, 50 mg/kg) in rats. Values are means ± SEM (n=6). **P < 0.01 and *P < 0.05 compared with TNBS-control group. TNBS, 2,4,6-trinitrobenzenesulfonic acid. Trop., tropisetron; mCPG, meta-chlorophenylbiguanide; Dex., dexamethasone. Stool consistency daily were checked in rats (1. Formed stools, 2. Loosed stools and 3. Diarrhea).