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. 2013 Sep 18;2(5):674–686. doi: 10.1002/cam4.133

Active/recruiting trials studying treatment approaches for metastatic uveal melanoma as registered on ClinicalTrials.gov.

ClinicalTrials.gov identifier Drug Phase Planned patients Status Sponsor
NCT01355120 Ipilimumab (anti-CTLA4 antibody) II 41 Data collection ongoing University Hospital Essen, Germany
NCT01034787 CP-675,206 (anti-CTLA4 antibody) II 32 Data collection ongoing Alberta Health Services, Canada
NCT01585194 Ipilimumab (anti-CTLA4 antibody) II 141 Recruiting MD Anderson Cancer Center, US
NCT01587352 Vorinostat (histone deacetylase inhibitor) II 32 Recruiting National Cancer Institute, US
NCT01413191 Cixutumumab (anti-IGF-1R antibody) II 32 Data collection ongoing National Cancer Institute, US
NCT01200342 Genasense/oblimersen (Bcl-2 antisense oligonucleotide) plus carboplatin/paclitaxel II 30 Data collection ongoing MD Anderson Cancer Center, US
NCT00506142 Marqibo (liposomal vincristine) II 50 Recruiting Talon Therapeutics, US
NCT00738361 Abraxane (nab-paclitaxel) II 25 Completed, results pending National Comprehensive Cancer Network, Ohio, US
NCT01252251 Everolimus (mTOR inhibitor) and pasireotide (somatostatin receptor analog) II 25 Recruiting Memorial Sloan-Kettering Cancer Center, US
NCT01200238 Ganetespib (HSP90 inhibitor) II 30 Recruiting Dana-Farber Cancer Institute, US
NCT01143402 Selumetinib (MEK inhibitor) versus temozolomide II 159 Recruiting National Cancer Institute, US
NCT01430416 AEB071 (protein kinase C inhibitor) I 65 Recruiting Novartis Pharmaceuticals, US
NCT01377025 Sorafenib versus placebo II 200 Recruiting University Hospital, Essen, Germany
NCT01801358 AEB071 (protein kinase C inhibitor) plus MEK162 I/II 90 Not yet recruiting Novartis Pharmaceuticals, US
NCT01835145 Cabozantinib versus temozolomide or dacarbazine II 69 Not yet recruiting National Cancer Institute, US