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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2003 May 8;285(3):H1132–H1139. doi: 10.1152/ajpheart.01141.2002

Fig. 7.

Fig. 7

Type I collagen mRNA analysis by Northern blot. ET-1 has a concentration-dependent effect on type I collagen gene expression. ET induction of myoFb type I collagen mRNA was determined by Northern hybridization (band sizes: top, 5.7 kb; bottom, 4.7 kb). Lane 1, untreated control. Lanes 2–5, treated with ET-1 (10−11 to 10−8 M). Lane 6, treated with ET-1 (10−9 M) and bosentan (10−6 M).