Table 3. 2012 polyanalgesic algorithm for intrathecal (IT) therapies in neuropathic pain 7.
| Line 1 | Morphine | Ziconotide | Morphine + bupivicaine | |
| Line 2 | Hydromorphone | Hydromorphone + bupivicaine
OR Hydromorphone + clonidine |
Morphine + clonidine | |
| Line 3 | Clonidine | Ziconotide + opioid | Fentanyl | Fentanyl + bupivicaine
OR Fentanyl + clonidine |
| Line 4 | Opioid + clonidine + bupivicaine | Bupivicaine + clonidine | ||
| Line 5 | Baclofen |
Note: Line 6- Experimental agents: Gabapentin, Octreotide, Conpeptide, Neostigmine, Adenosine, XEN 2174, AM 336, XEN, ZGX 160 (ongoing experiments in animal models).