Table 2.

Altered response in IFNγ and IL-6 cytokine release upon CD38 ligation in MM patients.^a

Stimulus	MM		Controls
	IFNγ (10)	IL-6 (10)	IFNγ (10)	IL-6 (10)
Anti-CD38	60 ± 19	2929 ± 878  P = 0.041	295 ± 156	820 ± 162
Anti-CD3	1072 ± 253	1638 ± 677	10361 ± 179	478 ± 99
None	45 ± 17	1088 ± 482	4.2 ± 1	236 ± 103

^aPBMC from MM patients and healthy individuals were treated with indicated stimulus and IFNγ and IL-6 assayed by specific ELISA. Results are expressed as mean ± SE of pg/mL. Number (n) of individuals tested and statistical significance (Student's t-test) of differences between MM and healthy controls are indicated.