Table 4.
Cox proportional hazard ratios for deaths relative to the first unbound free fatty acid quartile
| Quartilea | Hazard Ratio | CI (95%) | p Value | |
|---|---|---|---|---|
| Myocardial Infarction Deaths | ||||
| Unadjusted | Q2 | 2.3 | (0.9 – 5.9) | 0.094 |
| Q3 | 4 | (1.6 – 9.8) | 0.002 | |
| Q4 | 5.6 | (2.3 – 13) | < 0.001 | |
| Adjusted | Q2 | 2. 9 | (1.0 – 8.2) | 0.043 |
| Q3 | 4.2 | (1.6 – 11) | 0.002 | |
| Q4 | 5 | (1.9 – 13) | 0.001 | |
| All Cause Cardiac Deaths | ||||
| Unadjusted | Q2 | 1.7 | (0.9 – 3.1) | 0.103 |
| Q3 | 2.4 | (1.3 – 4.3) | 0.003 | |
| Q4 | 2.8 | (1.6 – 5.0) | 0.000 | |
| Adjusted | Q2 | 1.7 | (0·9 – 3.2) | 0.108 |
| Q3 | 2.1 | (1.2 – 4.0) | 0.015 | |
| Q4 | 2.4 | (1.3 – 4.4) | 0.004 | |
| All Cause Deaths | ||||
| Unadjusted | Q2 | 1.3 | (0.8 – 2.1) | 0.324 |
| Q3 | 1.9 | (1.2 – 3.0) | 0.004 | |
| Q4 | 2.2 | (1.4 – 3.4) | 0.001 | |
| Adjusted | Q2 | 1.3 | (0.8 – 2.1) | 0.374 |
| Q3 | 1.7 | (1.0 – 2.7) | 0.032 | |
| Q4 | 1.9 | (1.2 – 3.1) | 0.004 |
a
Cox proportional hazard model generated hazard ratios and corresponding 95 % confidence interval (CI) and Wald's χ2 probabilities. The model was adjusted for age, gender, race, body mass index, diastolic and systolic blood pressure at baseline, history of diabetes, MI and hypertension and use of β blockers within 24 hours of enrollment. This choice of factors was dictated by the limited access data set, known cardiac risk factors associated with more than 10 % of the 1834 patients and previous observed associations with free fatty acids.