Table 2. Some samples of sterols with relatively high affinities (docking score) to SlSCPx-2 protein.
Sterols | Docking score | Sterols | Docking score | Sterols | Docking score |
Epicholestenol | 11.64 | Desmosterol | 6.81 | Fungisterol | 6.14 |
Nandrolone | 8.91 | Avenasterol | 6.81 | 24-Epifungisterol | 6.12 |
β-ecdysone | 8.52 | α1-Sitosterol | 6.77 | Fucosterol | 6.14 |
α-Spinasterol* | 8.48 | Isocitrostadienol | 6.73 | a1-Sitosterol | 6.12 |
Clerosterol | 8.47 | Peposterol | 6.65 | β-Ergostenol | 6.12 |
Cholesterol * | 8.41 | Coprostane | 6.58 | Citrostadienol | 6.10 |
7-Dehydrositosterol | 8.03 | γ-ergostenol | 6.51 | 7-keto-campesterol | 6.09 |
Crinosterol | 8.00 | Chalinasterol | 6.42 | 22,23-Dihydrobrassicasterol | 6.08 |
β-Sitosterol* | 7.82 | 25-hydrochondrillasterol | 6.41 | Campesterol* | 6.05 |
Bufotoxin | 7.79 | Episterol | 6.40 | Methenolone | 6.04 |
5β,6β-epoxycholesterol | 7.69 | Squalamine | 6.39 | Ergosterol * | 5.98 |
γ-Sitosterol | 7.61 | α-ergostenol | 6.37 | 7α-hydroxycholesterol | 5.94 |
5-Stigmasten-3-one | 7.56 | 24,25-dimethyl-5α-cholesta-7,24(28)-dien-3β-ol | 6.31 | 7β-hydroxycholesterol | 5.94 |
7-Keto-β-sitosterol | 6.97 | 22-Dihydrochondrillasterol | 6.27 | Lumisterol* | 5.89 |
5,6-epoxy-β-sitosterol | 6.97 | 9,11-Dehydroergosterol | 6.21 | 9β-Ergosterol | 5.89 |
Spinasterol* | 6.91 | Neoergosterol | 6.18 | Coprostenol | 5.87 |
Chondrillasterol* | 6.90 | 4-stigmastene-3,6-dione | 6.16 | 5β-cholestane-3α,7α,12α-triol | 5.83 |
Dehydroergosterol | 6.89 | Stigmasterol * | 6.16 | Cycloeucalenol | 5.82 |
These sterols are commonly found in plants.