Skip to main content
. 2014 Jan 15;9(1):e83337. doi: 10.1371/journal.pone.0083337

Table 1. jpHMM-assigned breakpoint locations (with 95% confidence intervals) for five HIV-1 A1/D recombinant sequencesa.

Break point Study number Gene Region
33365 8179 40534 11762 12792
1 1162 (1154–1170) 1159 (1147–1171) 1167 (1148–1186) 1177 (1154–1200) 1156 (1141–1171) gag p24
2 1843 (1809–1877) 1844 (1809–1879) 1844 (1809–1879) 1958* (1811–2105) 1828 (1809–1847) gag p24
3 2089 (2047–2131) 2078 (2046–2110) 2078 (2046–2110) 2078 (2046–2110) 2056 (2002–2110) gag p1
4 2489 (2463–2515) 2489 (2465–2515) 2489 (2465–2515) 2487 (2475–2499) 2598 (2463–2733) pol PR
5 5981 (5951–6011) 5979 (5953–6005) 5976 (5951–6001) 5985 (5973–5997) 5998 (5989–6007) tat/rev
6 6551 (6543–6559) 6551 (6543–6559) 6551 (6543–6559) 6551 (6539–6563) 6551 (6543–6559) env gp120
7 7247 (7234–7260) 7246 (7231–7261) 7249 (7232–7266) 7483 (7471–7495) 7214 (7171–7257) env gp120
8 8679 (8664–8694) 8672 (8651–8693) 8679 (8663–8695) 8674 (8662–8686) 8678 (8663–8693) env gp41

a Breakpoint locations as determined by jpHMM with HXB2 numbering. The breakpoint locations are generally consistent across the five specimens, indicating that the same A1/D recombinant structure is shared.

This corresponds to a region of subtype D uncertainty;

This corresponds to a region of subtype A uncertainty; refer to Figure 1. PR = Protease.