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. Author manuscript; available in PMC: 2014 Mar 19.
Published in final edited form as: Nature. 2013 Aug 18;501(7467):426–429. doi: 10.1038/nature12447

Figure 3. B. fragilis requires the ccf genes for stable and resilient colonization of mice.

Figure 3

a, Groups of SPF Rag-/- mice were gavaged with either WT B. fragilis or B. fragilisΔCCF. b, SPF Rag-/- mice were given a 1:1 co-inoculum of WT B. fragilis and B. fragilisΔCCF by single gavage. c, SPF NOD mice were gavaged with either WT B. fragilis or B. fragilisΔCCF. d, SPF NOD mice were given a 1:1 co-inoculum of WT B. fragilis and B. fragilisΔCCF by single gavage. e, SPF mice were co-associated with WT B. fragilis and B. fragilisΔCCF, and infected with Citrobacter rodentium. f, SPF mice were co-associated with WT B. fragilis and B. fragilisΔCCF, and given ciprofloxacin in drinking water for the time period shown. For all analyses, bacterial colonization levels were assessed by real-time qRT-PCR from stool DNA (n=4 animals/group). Results are representative of at least 2 independent trials per experiments. Error bars indicate SEM.*p<0.05. ***p<0.001.