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. 2014 Jan 15;9(1):e84400. doi: 10.1371/journal.pone.0084400

Figure 3. Histological study and immunohistochemical analysis for PCNA (proliferating cell nuclear antigen) of gastric mucosa of rats treated with 1% Tween-80 aqueous solution (control), pantoprazole (40 mg/kg) and essential oil of Hyptis martiusii (EOHM, 400 mg/kg) for 14 days after injury induced by 30% acetic acid.

Figure 3

The filled arrow indicates the absence of the epithelial layer (ulcer area internal) and the dashed arrow indicates epithelial layer remaining (ulcer edge). Haematoxylin/eosin (HE) and Periodic Acid–Schiff staining (PAS), magnification, 40×. Microphotographs depict PCNA immunoreactivity in the groups, magnification, 200× (control) and 500× (pantoprazole or EOHM).