Table 1. Summary of top mutation types in each category enriched in drivers.

secondary structure	buried	interface	surface
coil	T→I
sheet	C→R,L→R
helix	L→R
any	C,H,L,W,Y,L→P,L→R,V→D	G,L,G→E,L→P,L→R,G→V,R→P	Y,L→R,G→V