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. 2014 Jan 15;9(1):e85461. doi: 10.1371/journal.pone.0085461

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© 2014 Ge et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Leukocyte analysis in mixed bone marrow chimeric wt (CD45.1)/Il17ra^-/- (CD45.2) mice. (A) The proportion of Il17ra^-/- cells among blood lymphocytes (Ly), granulocytes (PMN) and monocytes (mono). (B) Absolute monocyte concentrations for each genotype. (C,D) The proportion of Gr1^high (C, n = 20 mice from 3 independent transplantations) and Ly6C^high monocytes (D, n = 6) was significantly higher among Il17ra^-/- than wt cells. (E) Absolute blood monocyte concentrations (Bonferroni after One-way-ANOVA, n = 20 mice from 3 independent transplantations). (F) Proportion of blood monocytes staining as dead cells (n = 16 from 3 independent transplantations, Bonferroni after One-way-ANOVA)).