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. 2014 Jan 15;9(1):e85461. doi: 10.1371/journal.pone.0085461

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© 2014 Ge et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A-D) Mixed bone marrow chimeric wt/Il17ra^-/- mice underwent monocyte depletion by liposomal clodronate. During recovery, monocyte genotype (A), proportion of Gr1^high and Gr1^low cells among the monocytes of each genotype (B) and absolute blood concentrations of Gr1^high (C) and Gr1^low monocytes (D) of each genotype were measured (n = 8, 2 independent transplantations, Bonferroni after two-way-ANOVA).