Table 1. Correlation of Clinicopathological Characteristics with ABCC4 Expression in 121 LARC Patients Treated with Preoperative nRT.

Characteristics	Cases (n)	Expression of ABCC4 (n)		P value
		+/− (n = 53)	++/+++(n = 68)
Age				1.00
≤50 y	37	16	21
>50 y	84	37	47
Gender				.275
Female	59	29	30
Male	62	24	38
Tumor size				.461
≤5 cm	48	19	29
>5 cm	73	34	39
Gross type				1.00
Mass	30	13	17
Ulcerative	91	40	51
Differentiation				.366
Well	21	10	11
Moderate	72	34	38
Poor	28	9	19
CEA				.275
≤10 ng/ml	66	32	34
>10 ng/ml	55	21	34
CA19-9				.464
≤37 U/ml	58	23	35
>37 U/ml	63	30	33
T stage				.558
T3	83	38	45
T4	38	15	23
N stage				.392
N-	92	38	54
N+	29	15	14
p53 type				.856
Wild	58	26	32
Mutant	63	27	36

Abbreviations: ABCC4, ATP-binding cassette subfamily C member 4; CA19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; LARC, locally advanced rectal carcinoma; nRT, neoadjuvant radiotherapy.