Table 1. Modular recognition domains (MRDs).
| Target | MRD ID | Structure | Reference | Sequence |
|---|---|---|---|---|
| Ang2 | a1 | Disulfide Constrained | Zyngenia | LWDDCYFFPNPPHCYNSP |
| Ang2 | a2 | Linear | Zyngenia | DEHQTNFLPLDQDEALLYEEFILQQGLE |
| IGF1R | i1 | Affibody | Li, 2010 | VDNKFNKEGFYAAIEILALPNLNRKQSTAFISSLEDDPSQSANLLAEAKKLNDAQAPK |
| EGFR | e1 | Affibody | Gostring, 2010 | VDNKFNKEMWAAWEEIRNLPNLNGWQMTAFIASLVDDPSQSANLLAEAKKLNDAQAPK |
| ErbB3 | c1 | Affibody | Kronqvist, 2011 | VDNKFNKERYSAYYEIWQLPNLNVRQKAAFIGSLQDDPSQSANLLAEAKKLNDAQAPK |
| αvβ3 | n1 | Knottin | Kimura, 2009 | GCPQGRGDWAPTSCKQDSDCRAGCVCGPNGFCG |
MRDs used in zybody construction were adapted from the indicated references.