Figure 7. Free ligand concentration-time profiles following subcutaneous administration of anti-ligand Fab to Sprague-Dawley rats at doses of 0 (circles), 0.03 (squares), 0.1 (triangles), 0.3 (diamonds) or 1 (inverted triangles) mg/kg. Samples were pooled across a group of 6 rats at each time point prior to analysis. Samples below the lower limit of quantitation (LLOQ) are plotted at the limit of quantitation for visualization purposes.