Figure 1. Delineation of five critical regions for cardiovascular malformations on 1p36.
Solid bars represent isolated 1p36 deletions identified in individuals with cardiovascular malformations. These deletions are grouped based on the source from which data was obtained: 1) patients referred to the Medical Genetics Laboratories at Baylor College of Medicine for copy number analysis and 2) patients recruited into a research study on 1p36 deletions at Baylor College of Medicine [orange], 3) the DECIPHER database [blue], and 4) a review of the literature [green]. Deletions that define non-overlapping critical region for cardiovascular malformation are shown in red and are numbered sequentially from the telomere.