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Permeability measurements for mice (n = 3) injected with Definity® (black) and in-house polydisperse (IHP) microbubbles (red) with various sonication peak rarefactional pressures (PRPs). Significant difference (T-test, p < 0.01) was found only between the two groups sonicated at the PRP of 0.3 MPa (indicated by asterisk).
