FIG. 1.

Principle and overview of the histology slide probe. a: Schematic of the planar coil structure to accommodate histology tissue section. The choice of the width (W) defines the extent of the homogeneous RF field of interest covering the tissue sample to be imaged within a slide. b: The height (H) of the opening was chosen to insert a tissue encasing slide setup to accommodate the pairing of either a glass/coverslip (~1350 μm) or two coverslips (~450 μm). c: The inner length (IL) comes in two dimensions to house commercially available 12-mm-wide coverslips or 25-mm-wide slides. The resulting OL of the probe is approximately twice the IL as prescribed by Meadowcroft et al. (2007). For the sake of simplicity of the design, the construction of the structures described in this work was made in-house using thermo-glue as in (b and d). e: The current traversing the slotted resonator induces a transverse B1 RF field after crossing a square Teflon-based capacitive insert extending throughout the whole unused but required OL of the coil. f: The tuning/matching (T/M) of all the probes is insured by two variable capacitors (Voltronics Corps., Salisbury, MD) via a double-shielded coaxial cable. All probes can be easily interchanged with the same T/M circuit.