A: 10 μM OXO evoked maximum rise in [Ca2+]i in NB-, OAB-, and DFMO-treated OAB and DFMO + MGBG-treated NB and DFMO + MGBG-treated OAB BUC. **P < 0.01 vs. NB, §§P < 0.01 vs. NB, ##P < 0.01 vs. OAB. B: percentage of BUC that responded (see methods for definition of responsive cells) to 10 μM OXO stimulation in NB-, OAB-, DFMO-treated OAB and DFMO + MGBG-treated NB and DFMO + MGBG-treated OAB BUC, *P < 0.05, §§P < 0.01 vs. NB, ##P < 0.01 vs. OAB. Cells were from 3 OAB and 3 NB subjects.