Table 1.
Clinical and biochemical characteristics of the study subjects
| Clinical parameters |
Control (NGT) |
T2DM |
CAD |
T2DM_CAD |
|---|---|---|---|---|
| n = 61 | n = 60 | n = 23 | n = 21 | |
| Age (Years) |
39.6 ± 13.7 |
56.4 ± 13.9a*** |
38.7 ± 15.8 |
60.9 ± 10.7c*** |
| Body mass index (kg/m2) |
23.19 ± 4.8 |
25.5 ± 5.2 |
21.1 ± 4.3 |
23.2 ± 4 |
| Systolic BP (mm Hg) |
114 ± 9.5 |
125 ± 2.2a** |
122.5 ± 20.6 |
142.4 ± 19.9b**c** |
| Diastolic BP (mm Hg) |
74.98 ± 8.5 |
77.2 ± 9.0 |
71.8 ± 10.03 |
87.3 ± 11.04b* |
| Fasting plasma glucose (mg/dL) |
84.9 ± 9.1 |
158.9 ± 67.5a*** |
85.8 ± 12.5 |
136.2 ± 41.4c*** |
| Glycated haemoglobin (%) |
5.3 ± 0.37 |
8.5 ± 1.9a*** |
5.4 ± 0.5 |
7.6 ± 0.8c** |
| Total serum cholesterol (mg/dL) |
174.5 ± 34.08 |
173.3 ± 46.02 |
188.2 ± 81.2 |
182.3 ± 37.1 |
| Serum triglycerides (mg/dL) |
108.2 ± 51.1 |
168.4 ± 100.4a*** |
105.1 ± 54.6 |
140.1 ± 77.4 |
| HDL-cholesterol (mg/dL) |
43 ± 7.9 |
40 ± 9.1 |
47.7 ± 12.6 |
41.9 ± 11.9 |
| LDL-cholesterol (mg/dL) |
107.7 ± 28.7 |
98.5 ± 37.9 |
119.5 ± 73.4 |
112.4 ± 33.3 |
| VLDL-cholesterol (mg/dL) |
20.2 ± 9.4 |
49.6 ± 51.5a*** |
20.9 ± 10.8 |
23.5 ± 11.4 |
| Urea |
20.5 ± 5.2 |
23.5 ± 8.7 |
20.8 ± 5.7 |
22.3 ± 4.1 |
| Creatinine |
0.85 ± 0.16 |
4.6 ± 11.7 |
0.8 ± 0.16 |
0.8 ± 0.24 |
| Microalbuminuria (mg/dL) | 16.4 ± 48.4 | 22.1 ± 33.9 | 15.1 ± 20.2 | 15 ± 16.4 |
For all the parameters mean ± SD is reported. aComparison between Control and T2DM, bComparison between T2DM and T2DM-CAD, cComparison between CAD and T2DM-CAD. *P < 0.05, **P < 0.01, ***P < 0.0001.