Table 1.
Patients demographics and clinical presentation of the aneurysms studied for lipid accumulation and oxidized lipids
| Variables | Bleeding status | P-value | |
|---|---|---|---|
| |
Unruptured
|
Ruptured
|
|
|
(n = 18) |
(n = 36) |
||
|
A.Patients
|
|
|
|
| Age (years) |
55y. (42–70) |
57y. (34–84) |
0.773 |
| Gender (females) |
56% (10/18) |
72% (26/36) |
0.239 |
| Patients with multiple sIAs (≥2) |
33% (6/18) |
36% (13/36) |
1.000 |
| History of prior SAH (from the studied sIA or another sIA) |
20% (3/15) |
97% (35/36) † |
<0.001* |
| Familial background |
|
|
0.174 |
| Documented familial background (sIAs) |
0% (0/18) |
8% (3/36) |
|
| Possible familial background # |
11% (2/18) |
11% (4/36) |
|
| Family history unknown |
39% (7/18) |
58% (21/36) |
|
| No familial background (verified cases) |
50% (9/18) |
22% (8/36) |
|
| Smoking |
|
|
0.129 |
| Current smoker |
50% (9/18) |
39% (14/36) |
|
| Ex-smoker |
17% (3/18) |
3% (1/36) |
|
| Never smoked |
17% (3/18) |
17% (6/36) |
|
| Status not known |
17% (3/18) |
42% (15/36) |
|
| Hypertension |
83% (15/18) |
36% (13/36) |
0.004* |
|
B.Aneurysms
|
|
|
|
| Neck diameter (mm) |
4.5 mm (3–7) |
4 mm (1.5-8) |
0.273 |
| Width of fundus (mm) |
6.0 mm (3–11) |
7.0 mm (3–19) |
0.624 |
| Lenght of fundus (mm) | 6.3 mm (3–11) | 6.5 mm (2–27) | 0.773 |
Median and range are given for continuous variables, proportions for categorical variables. Mann–Whitney U-test was used for continous and Fisher’s Exact test for categorical variables. P-values <0.05 are marked with *.
† One of the ruptured aneurysms presented in the operation with old thrombus and hemosiderin surrounding the aneurysm although the patient had not been diagnosed with SAH and had not had any symptomps suggesting SAH.
# When patients had multiple relatives that had been diagnosed with intracranial hemorrhage but the etiology of the hemorrhage was not clear.