Table 2.
Comorbidities, clinical features, and treatment outcomes of EPTB and PTB in Brazil, 2007- 2011
| Characteristics N* | Categories | EPTB (%) (n = 53,853) | PTB (%) (n = 356,341) | P value** |
|---|---|---|---|---|
| HIV/AIDS |
Negative |
24,072 (69.2) |
149,526 (83.8) |
<0.001 |
| (213,336) |
Positive |
10,755 (30.8) |
28,983 (16.2) |
|
| Alcoholism |
No |
46,056(91.6) |
249,995 (82.0) |
<0.001 |
| (355,292) |
Yes |
4,236 (8.4) |
55,005 (18.0) |
|
| Diabetes |
No |
48,121 (96.1) |
279,415 (92.9) |
<0.001 |
| (350,756) |
Yes |
1,960 (3.9) |
21,260 (7.1) |
|
| Mental illness |
No |
49,114 (98.1) |
293,039 (97.3) |
<0.001 |
| (351,236) |
Yes |
960 (1.9) |
8,123 (2.7) |
|
| Other diseases |
No |
38,142 (83.8) |
229,706 (84.7) |
0.001 |
| (316,784) |
Yes |
7,357 (16.2) |
41,579 (15.3) |
|
| Admission type |
New cases |
50,126 (87.6) |
290,431 (81.5) |
<0.001 |
| (413,559) |
Relapse |
2,178 (3.8) |
23,013 (6.5) |
|
| |
Readmission after dropout |
1,386(2.4) |
23,191 (6.5) |
|
| |
Unknown |
151 (0.3) |
1,026 (0.3) |
|
| |
Transfer |
3,376 (5.9) |
18,681 (5.2) |
|
| TST |
Negative |
4,745 (29.3) |
14,461 (28.0) |
<0.001 |
| (67,942) |
Positive |
11,481 (70.7.2) |
37,255 (72.0) |
|
| AFB smear |
Negative |
23,936 (80.0) |
82,602 (26.5) |
<0.001 |
| (341,807) |
Positive |
5,997 (20.0) |
229,272 (73.5) |
|
| Culture |
Negative |
6,775 (59.3) |
22,103 (33.2) |
<0.001 |
| (78,004) |
Positive |
4,648 (40.7) |
44,478 (66.8) |
|
| Histopathology |
Negative |
884 (3.8) |
2,184 (9.9) |
<0.001 |
| (44,855) |
Positive |
21,903(96.2) |
19.884 (90.1) |
|
| DOT |
Not performed |
28,727 (64.7) |
153.811 (51.7) |
<0.001 |
| (341,831) |
Performed |
15,696 (35.3) |
143,597 (48.3) |
|
| Outcome status |
Cure |
30,186(71.5) |
186,428 (70.1) |
<0.001 |
| (308,112) |
Dropout |
3,429 (8.1) |
33,016 (12.4) |
|
| |
Death by TB |
1,564 (3.7) |
10,718 (4.0) |
|
| |
Death by other causes |
3,024 (7.2) |
11,046 (4.2) |
|
| |
Transfer |
3,967 (9.4) |
23,566 (8.9) |
|
| MDR-TB | 28 (0.1) | 1,140 (0.4) |
*Number of valid observations. **Pearson’s chi-squared test.
HIV/AIDS: human immunodeficiency virus/acquired immunodeficiency syndrome. TST: tuberculin skin test. AFB: acid-fast bacilli. DOT: Directly Observed Therapy. EPTB: Extrapulmonary tuberculosis. PTB: pulmonary tuberculosis.