Table 1.

Demographic and clinical characteristics of CPM patients

No.	Age	Sex	AQP1/4 tissue	Brief history	Probable cause/
	(years)		immunoreactivity*		underlying cause of
					CPM
1	56	M	0	Alcoholism; nausea and vomiting 1 week; hyponatremia, abnormal liver function tests; presented to Emergency Room in cardiorespiratory arrest.	Rapid correction of hyponatremia
2	53	M	0	Depression and chronic obstructive pulmonary disease. Not seen for 4 days; found dehydrated and malnourished; drug and alcohol screen negative.	Dehydration, malnutrition and hypernatremia
3	33	M	0	Cryptogenic cirrhosis with antitrypsin heterozygosity; orthotopic liver transplant and hyponatremia followed by progressive obtundation and seizures.	Orthotopic liver transplant
4	45	M	0	Small-cell lung carcinoma, metastatic to liver; abnormal liver function tests; possible malnutrition; hyperkalemia; several syncopal episodes in preceding hours; presented with respiratory failure.	SIAD secondary to small-cell lung carcinoma
5	24	F	↑	Hepatic failure and autoimmune thrombocytopenic purpura, 6 months; altered consciousness level and nonconvulsive status epilepticus 5 weeks before death; hypocalcemia, hyperammonemia and elevated liver enzymes.	Hepatic failure and hypocalcemia
6	68	F	↑	Hypertension, obesity, diabetes mellitus, hyperuricemia and remote endometrial carcinoma (treated by resection, chemotherapy, and radiotherapy); presented with gangrene of the right fifth toe; generalized seizure followed by unresponsiveness.	Diabetes mellitus type II

*0 = absent; ↑ = increased.