Table 3.

Adjusted association measured between seafood consumption and wheeze, eczema and food allergy

		Probable wheeze	Certain wheeze	Eczema	Food allergy
		OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
Complete-case analysis
Fish consumption*		1398		1395	1395
	<1 time a month	1	1	1	1
	1–4 times a month	0.83 (0.58-1.17)	0.69 (0.45-1.05)§	1.06 (0.77-1.48)	1.27 (0.72-2.24)
	≥2 times a week	1.04 (0.70-1.55)	0.90 (0.56-1.44)	0.89 (0.61-1.29)	1.48 (0.80-2.76)
Shellfish consumption*
	<1 time a month	1	1	1	1
	≥1 time a month	1.08 (0.83-1.40)	1.08 (0.78-1.49)	1.09 (0.85-1.40)	1.62 (1.11-2.37)‡
Fish consumption**
	<1 time a month	1	1	1	1
	1–4 times a month	0.82 (0.57-1.17)	0.68 (0.45-1.04)§	1.04 (0.75-1.45)	1.16 (0.65-2.07)
	≥2 times a week	1.02 (0.68-1.54)	0.87 (0.54-1.42)	0.85 (0.58-1.25)	1.27 (0.67-2.39)
Shellfish consumption**
	<1 time a month	1	1	1	1
	≥1 time a month	1.06 (0.81-1.39)	1.08 (0.77-1.51)	1.13 (0.87-1.45)	1.57 (1.06-2.31)‡
Multiple imputation analysis
Fish consumption**		2981		2981	2981
	<1 time a month	1	1	1	1
	1–4 times a month	0.90 (0.69-1.17)	0.86 (0.63-1.17)	1.03 (0.76-1.39)	1.13 (0.70-1.83)
	≥2 times a week	1.07 (0.78-1.47)	1.11 (0.75-1.67)	0.92 (0.58-1.46)	1.37 (0.79-2.39)
Shellfish consumption**
	<1 time a month	1	1	1	1
	≥1 time a month	1.02 (0.80-1.31)	1.02 (0.81-1.30)	1.01 (0.76-1.34)	1.52 (1.05-2.21)‡

*Adjusted for: mother’s age, maternal education, folic acid supplementation, familial history of asthma/allergy, child’s sex, small-for-gestational age, infant’s method of feeding, day care attendance, post-natal exposure to tobacco and, child’s age at follow-up.

**Both fish and shellfish consumption were included in the model with the adjustment variables above.

§ p-value < 0.10; ‡ p-value < 0.05.