Table 4.
Results of multiple linear regression analysis of the associations between natural log transformed serum concentrations of groups of PCB congeners differing by the number of ortho- substituted chlorines and the various lipid fractions (n = 575)
| |
Mono-ortho |
Di-ortho |
Tri-/Tetra-ortho |
||||
|---|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | ||
| Total lipids |
β |
0.04 |
−0.05 |
0.05 |
−0.09 |
0.06 |
0.12 |
| p-value |
0.0005 |
0.0814 |
<0.0001 |
0.0433 |
<0.0001 |
<0.0001 |
|
| SP R22 |
0.0193 |
0.0040 |
0.0245 |
0.0053 |
0.0391 |
0.0209 |
|
| Total Cholesterol |
β |
0.03 |
−0.02 |
0.03 |
−0.08 |
0.04 |
0.09 |
| p-value |
0.0262 |
0.5254 |
0.0169 |
0.0846 |
0.0013 |
0.0047 |
|
| SP R22 |
0.0081 |
0.0001 |
0.0094 |
0.0044 |
0.0169 |
0.0120 |
|
| HDL cholesterol |
β |
0.01 |
0.08 |
−0.00 |
−0.05 |
−0.00 |
−0.02 |
| p-value |
0.4722 |
0.0297 |
0.9741 |
0.4145 |
0.8036 |
0.6888 |
|
| SP R22 |
0.0008 |
0.0072 |
0.0000 |
0.0010 |
0.0001 |
0.0010 |
|
| LDL cholesterol |
β |
0.02 |
−0.03 |
0.02 |
−0.09 |
0.04 |
0.11 |
| p-value |
0.2997 |
0.4565 |
0.1728 |
0.2056 |
0.0285 |
0.0133 |
|
| SP R22 |
0.0018 |
0.0009 |
0.0032 |
0.0026 |
0.0082 |
0.0099 |
|
| Triglycerides |
β |
0.08 |
−0.16 |
0.09 |
−0.20 |
0.12 |
0.31 |
| p-value |
0.0117 |
0.0219 |
0.0018 |
0.0754 |
<0.0001 |
<0.0001 |
|
| SP R22 | 0.0099 | 0.0069 | 0.0152 | 0.0042 | 0.0279 | 0.0211 | |
Model 1: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, but not adjusted for the two remaining PCB groups and chlorinated pesticides.
Model 2: The estimates are adjusted for age (as well as age quadratic), race, gender, BMI, alcohol consumption, smoking and exercising status, and adjusted for the remaining two PCB groups and chlorinated pesticides.
SP R22 – Type II semi-partial R2.