Table 1.
Rash rating scales used in this investigation
| Grade | EGFR-Inhibitor induced rash scale | CTCAE Assessment scale |
|---|---|---|
| 0 |
No rash |
No rash |
| 1 |
Isolated pustule or erythematous patch < 1 cm in diameter, on either face/head/neck or chest/back |
Macular or papular eruption or erythema without associated symptoms |
| 2 |
More than one erythematous patch or erythema and telangiectasia on either face/head/neck or chest/back |
Macular or papular eruption or erythema with pruritus or other associated symptoms; localized desquamation or other lesions covering < 50% of body surface area |
| 3 |
More than one pustule or papules on either face/head/neck or chest/back with no associated erythema or telangiectasia |
Severe, generalized erythroderma or macular, papular or vesicular eruption; desquamation covering ≥ 50% body surface area |
| 4 |
Both erythema/telangiectasia and pustules/papules limited to either face/head/neck or chest/back |
Generalized exfoliative, ulcerative, or bullous dermatitis |
| 5 | Pustules or papules and erythema/telangiectasia present on both the face/head/neck region and the chest/back | Death |