Table 1.
Baseline characteristics
| Characteristic | Total (n=88) | Biocompatible (n=42) | Control (n=46) | P values |
|---|---|---|---|---|
| Age (yr) |
62 (51–69) |
64 (51–70) |
60 (51–67) |
0.28 |
| Female |
39 (44.32) |
18 (42.86) |
21 (45.65) |
0.79 |
| Ethnicity |
|
|
|
0.21 |
| - Caucasian |
65 (73.86) |
34 (80.95) |
31 (67.39) |
|
| - ATSI |
3 (3.41) |
1 (2.38) |
2 (4.35) |
|
| - Asian |
16 (18.18) |
7 (16.67) |
9 (19.57) |
|
| - MPI |
4 (4.55) |
0 (0) |
4 (8.69) |
|
| Diabetes Mellitus |
28 (31.82) |
12 (28.57) |
16 (34.78) |
0.53 |
| Primary renal disease |
|
|
|
0.16 |
| - Glomerulonephritis |
21(23.86) |
9 (21.43) |
12(26.09) |
|
| - Diabetic nephropathy |
22 (25.00) |
7 (16.67) |
15 (32.61) |
|
| - Hypertensive/Renovascular |
15 (17.05) |
7 (16.67) |
8 (17.39) |
|
| - Polycystic kidney disease |
8 (9.09) |
5 (11.90) |
3 (6.52) |
|
| - Reflux nephropathy |
4 (4.55) |
4 (9.52) |
0 (0.00) |
|
| - Other |
18 (20.45) |
10 (23.81) |
8 (17.39) |
|
| Body mass index (kg/m2) |
|
|
|
0.54 |
| - <20 |
2 (2.27) |
0 (0) |
2 (4.35) |
|
| - 20-24.9 |
25 (28.41) |
13 (30.95) |
12 (26.09) |
|
| - 25-30 |
32 (36.36) |
16 (38.10) |
16 (34.78) |
|
| - >30 |
29 (32.95) |
13 (30.95) |
16 (34.78) |
|
| Haemodialysis before PD |
4 (4.55) |
2 (4.76) |
2 (4.35) |
0.93 |
| Initial PD modality |
|
|
|
0.79 |
| - CAPD |
81 (92.05) |
39 (92.86) |
42 (91.30) |
|
| - APD |
7 (7.95) |
3 (7.14) |
4 (8.70) |
|
| GFR (mL/min per 1.73 m2) |
7.40 ± 2.85 |
7.28 ± 2.58 |
7.51 ± 3.09 |
0.72 |
| Urine volume (mL/day) |
1379.50 (1057.5-1900) |
1573 (1060–2059) |
1325 (1055–1810) |
0.25 |
| 7.5% Icodextrin use (%) |
11 (12.50) |
5 (11.90) |
6 (13.04) |
0.87 |
| Ultrafiltration# (mL/day) |
959.50 (510–1400) |
800 (430–1300) |
1050 (773–1500) |
0.03 |
| Normalized ultrafiltration corrected for total glucose exposure# |
4.08 (2.21-6.04) |
3.18 (1.78-4.19) |
4.59 (3.17-7.45) |
0.002 |
| Total glucose exposure (g/day) |
122.52 ± 32.44 |
122.38 ± 32.35 |
122.65 ± 32.90 |
0.97 |
| D:PCr4h* |
0.64 ± 0.10 |
0.67 ± 0.11 |
0.61 ± 0.09 |
0.006 |
| IL-6 (pg/mL) |
7.22 (3.93-13.71) |
7.61 (4.66-19.98) |
6.42 (3.29-9.63) |
0.17 |
| IL-6 Appearance rate^ | 23.19 (13.66-59.35) | 27.14 (14.12-67.27) | 21.90 (13.66-35.01) | 0.45 |
#Measured at month 3; *Measured at month 1; ^IL-6 appearance rate = IL-6*effluent volume/dwell time in minutes.
APD: automated peritoneal dialysis; ATSI: Aboriginal and Torres Strait Islander; CAPD: continuous ambulatory peritoneal dialysis; D:PCr4h: dialysate:plasma creatinine ratio measured at 4 hours; GFR: glomerular filtration rate; IL-6: interleukin-6; MPI: Maori & Pacific Islander; PD: peritoneal Dialysis.