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Immunohistochemical groupings of medulloblastoma tumors
| |
|
β-catenin |
|
|---|---|---|---|
| Nuclear + Cytoplasmic | Cytoplasmic | ||
| YAP1 |
Positive |
MB5, MB8, MB15, MB35 |
MB2, MB6, MB24, MB34, MB38 |
| |
WNT |
SHH |
|
| |
Negative |
|
MB1, MB3, MB4, MB7, MB13, MB14, MB18, MB25, MB26, MB27, MB28, MB29, MB30, MB31, MB32, MB33, MB36, MB37, MB39, MB40, MB41, MB42 |
| Non-WNT/SHH | |||
* MB28 and MB37 displayed rare nuclei that were weakly positive for YAP1; both were considered negative for YAP1 immunoreactivity.
