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Dose dependent anti-proliferative effect of A) VAE-M and B) VAE-Q and effect of VAE-M on C) early and E) late apoptosis/necrosis and of VAE-Qu on D) early and F) late apoptosis/necrosis of five cancer cell lines. Results are presented as mean ± SD from three independent experiments. Cell growth kinetic was assessed with the WST-1 assay. Apoptosis was measured by flow cytometric analysis of Annexin V-FITC and 7-AAD double-labeled cells.
