Table 1.
Cell lines, chemotherapeutic drug concentrations and incubation times used for the proliferation and apoptosis/necrosis assays
| Cell line | Chemotherapeutic drug |
Concentrations of chemotherapeutic drug (μg/ml) for |
Incubation time (h) | |
|---|---|---|---|---|
| Proliferation assay | Apoptosis assay | |||
| HCC1937 |
Doxorubicin hydroxide |
0.0; 0.1; 0.5; 1.0; 5.0 |
0.0; 0.25; 1.0; 5.0 |
48 |
| HCC1143 |
Doxorubicin hydroxide |
0.0; 0.1; 0.5; 1.0; 5.0 |
0.0; 0.5; 5.0 |
48 |
| PA-TU-8902 |
Gemcitabine hydroxide |
0.0; 0.01; 0.1; 1.0; 10.0 |
0.0; 25.0; 50.0; 100.0; 200.0 |
72 |
| DU-145 |
Docetaxel |
0.0; 0.0008; 0.008; 0.08; 0.8 |
0.0; 0.0008; 0.008; 0.08; 0.8 |
72 |
| DU-145 |
Mitoxantrone hydroxide |
0.0; 0.002; 0,02; 0,2; 2.0 |
0.0; 0.002; 0,02; 0,2; 2.0 |
72 |
| NCI-H460 |
Cisplatin |
0.0; 0.3; 1.0; 3.0; 9.0 |
0.0; 0.3; 1.0; 3.0; 9.0 |
48 |
| NCI-H460 | Docetaxel | 0.0; 0.001; 0.01; 0.1; 1.0 | 0.0; 0.001; 0.01; 0.1; 1.0 | 48 |