Table 3.

ApEn and Cross-ApEn: Summary Data for 0000h to 1000h Time Series.

	Control Group (N = 11)	Depressed High Cortisol (N = 7)	Depressed Low Cortisol (N = 5)	P values
				ANOVA	Kruskal-Wallis
Day 1 (Placebo)
ACTH ApEn	1.3546 ± 0.0293 (1.3532)	1.3714 ± 0.0455 (1.3720)	1.3796 ± 0.0397 (1.3821)	0.89	0.80
Cortisol ApEn	1.2458 ± 0.0217A (1.2343)	1.3986 ± 0.0381B (1.4249)	1.2046 ± 0.0553A (1.2093)	0.004	0.008
ACTH-Cortisol X-ApEn	1.6875 ± 0.0274AB (1.7022)	1.8155 ± 0.0292A (1.8361)	1.6051 ± 0.0664B (1.6678)	0.007	0.011
Cortisol-ACTH X-ApEn	1.6895 ± 0.0544 (1.6552)	1.8161 ± 0.0367 (1.8126)	1.6066 ± 0.0543 (1.6393)	0.074	0.069
Day 2 (Metyrapone)
ACTH ApEn	1.0199 ± 0.0772 (0.9760)	1.0405 ± 0.0771 (1.0040)	1.0055 ± 0.0858 (0.9985)	0.95	0.95
Cortisol ApEn	1.3902 ± 0.0292 (1.3665)	1.3607 ± 0.0285 (1.3613)	1.3233 ± 0.0525 (1.2823)	0.43	0.59
ACTH-Cortisol X-ApEn	1.6625 ± 0.0651 (1.7143)	1.7467 ± 0.0857 (1.8686)	1.4546 ± 0.1128 (1.5193)	0.096	0.23
Cortisol-ACTH X-ApEn	1.6619 ± 0.0520 (1.6152)	1.6617 ± 0.0490 (1.6352)	1.5263 ± 0.0843 (1.4848)	0.24	0.27

Data are mean ± SEM (median) for 10h period 0000h to 1000h on each day.

ApEn and cross-ApEn (X-ApEn) are unitless.

Differing alphabetical superscripts denote statistical differences according to post hoc Tukey’s HSD test.