Table 2.
Severity of symptomatic knee osteoarthritis (SKOA) according to clinical and radiographic measures: pain visual analog scale (VAS) and Western Ontario and McMaster Osteoarthritis Index (WOMAC) scores at baseline; change in Kellgren-Lawrence (KL) grade from baseline to 24 months; joint space width (JSW) at baseline and 24 months; and progression of joint space narrowing (JSN) at 24 months
| Variables | OA ( N = 120) | Female ( N = 76) | Male ( N = 44) |
|---|---|---|---|
| VAS Pain, mean ± SD (0-100 mm) |
40.21 ± 24.6 |
42.3 ± 24.5 |
37.4 ± 29.6 |
| WOMAC, mean ± SD |
170.25 ± 105.2 |
173.6 ± 104.2 |
164.5 ± 107.6 |
| KL delta from baseline to 24 months, N (%) |
|
|
|
| -1 |
3 (2.5%) |
2 (2.6%) |
1 (2.3%) |
| 0 |
88 (73.3%) |
56 (73.7%) |
32 (72.7%) |
| 1 |
26 (21.6%) |
16 (21.1%) |
10 (22.7%) |
| 2 |
2 (1.7%) |
2 (2.6%) |
0 |
| 3 |
1 (8.3%) |
0 |
1 (2.3%) |
| JSW at baseline, mean ± SD (mm) |
3.272 ± 1.766 |
3.603 ± 1.58 |
2.7 ± 1.93 |
| JSW at 24 months, mean ± SD (mm) |
2.989 ± 1.761 |
3.388 ± 1.513 |
2. 3 ± 1.956 |
| JSN over 24 months, mean ± SD (mm) | 0.283 ± 0.996 | 0.21 ± 0.88 | 0.4 ± 1.16 |