Table 4.
Univariate and multivariate analyses in the osteoarthritis (OA) population for relationship between serum ferritin level and demographical, clinical, and radiographic variables at entry
| Variables: All OA ( N = 120) |
Serum ferritin |
P value* |
Odds ratio |
Adjusted Odds ratio |
|---|---|---|---|---|
| (ng/ml), mean ± SD | [95% CI; P value**] | [95% CI; P value***] | ||
| Sex: |
|
|
|
|
| Female (N = 76) |
37.79 ±33.3 |
0.0001 |
4.1 |
NA |
| Male (N = 44) |
65.3 ±45.0 |
|
[CI: 1.76–9.87; P = 0.0004] |
|
| Age (years): |
|
|
|
|
| ≤74 (N = 105) |
45.8 ±39.8 |
0.047 |
3.48 |
NA |
| >74 (N = 15) |
61.9 ±40.8 |
|
[CI: 0.99–14.01; P = 0.045] |
|
| JSW (mm) baseline: |
|
|
|
|
| >4 (N = 80) |
34.4 ±30.0 |
0.032 |
3.2 |
2.66 |
| ≤4 (N = 40) |
54.6 ±42.9 |
|
[CI: 1.29–8.78; P = 0.006] |
[CI: 1.07–6.64; P = 0.035] |
| KL severity baseline: |
|
|
|
|
| KL2 (N = 18) |
46.3 ±40.6 |
0.975 |
1.505 |
1.63 |
| KL3/4 (N = 72) | 48.6 ±39.7 | [0.459–5.459; P = 0.5943] | [0.54–5.00; P = 0.3859] |
*t test on log ferritin.
**Chi-square test on dichotomized ferritin levels at third quintile.
***Logistic regression with adjustment for body mass index (BMI), age, sex.