Table 1.
Baseline Characteristics
| Derivation (n=22,096) |
Validation (n=11,048) |
|
|---|---|---|
| Age, y | 61 (50–79) | 61 (50–79) |
| Ethnicity | ||
| White | 18,395 (83%) | 9,172 (83%) |
| Black | 1,792 (8%) | 925 (8%) |
| Hispanic | 975 (4%) | 511 (5%) |
| American Indian | 94 (0%) | 31 (0%) |
| Asian/Pacific Islander | 541 (2%) | 270 (2%) |
| Unknown | 299 (1%) | 139 (1%) |
| Smoking | ||
| Never smoked | 11,436 (52%) | 5,738 (52%) |
| Past smoker | 9,018 (41%) | 4,463 (40%) |
| Current smoker | 1,642 (7%) | 847 (8%) |
| Hypertension | 5,715 (26%) | 2,839 (26%) |
| Treated Diabetes | 628 (3%) | 344 (3%) |
| Systolic Blood Pressure, mmHg | 124 (113 to 135) | 124 (113 to 135) |
| Diastolic Blood Pressure, mmHg | 75 (70 to 81) | 75 (70 to 81) |
| Body Mass Index, kg/m2 | 27.5 (24.3 to 31.3) | 27.4 (24.4 to 31.5) |
| Statin Use | 1,116 (5%) | 538 (5%) |
| Other Antihyperlipidemic Medication Use | 1,304 (6%) | 634 (6%) |
| Aspirin Use | 4,013 (18%) | 1,987 (18%) |
| Bilateral Oophorectomy | 3,370 (17%) | 1936 (18%) |
| Hysterectomy | 8,430 (38%) | 4,308 (39%) |
| Waist-to-Hip Ratio | 0.80 (0.76 to 0.85) | 0.80 (0.76 to 0.85) |
| Pregnancy | ||
| Never Pregnant | 1864 (8%) | 929 (8%) |
| 1 | 1,534 (7%) | 751 (7%) |
| 2–4 | 13,129 (59%) | 6,550 (59%) |
| 5+ | 5,569 (25%) | 2,818 (26%) |
| HRT Usage Status | ||
| Never Used | 10,210 (46%) | 5,089 (46%) |
| Past User | 3,763 (17%) | 1,810 (16%) |
| Current User | 8,123 (37%) | 4,149 (38%) |
| Income | ||
| Less than $10,000 | 807 (4%) | 373 (3%) |
| $10,000 to $19,999 | 2,285 (10%) | 1,206 (11%) |
| $20,000 to $34,999 | 4,997 (23%) | 2,446 (22%) |
| $35,000 to $49,999 | 5,198 (24%) | 2,575 (23%) |
| $50,000 to $74,999 | 4,410 (20%) | 2,233 (20%) |
| $75,000 to $99,999 | 2,023 (9%) | 1,012 (9%) |
| $100,000 to $149,999 | 1,288 (6%) | 639 (6%) |
| $150,000 or more | 623 (3%) | 285 (3%) |
| Unknown | 465 (2%) | 279 (3%) |
| Alcoholic Drinks Per Week | 0.4 (0-2.7) | 0.4 (0–2.7) |
| Marital Status | ||
| Never Married | 908 (4%) | 463 (4%) |
| Divorced / Separated | 3490 (16%) | 1,813 (16%) |
| Widowed | 3270 (15%) | 1,685 (15%) |
| Presently married / Living as married | 14428 (65%) | 7,087 (64%) |
| Medical Insurance | 20,716 (94%) | 10,372 (94%) |
| Education | ||
| 0–8 Years | 293 (1%) | 158 (1%) |
| Some high school | 715 (3%) | 342 (3%) |
| High School Diploma / GED | 3,958 (18%) | 1,871 (17%) |
| School After High School | 8,714 (39%) | 4,283 (39%) |
| College Degree Or Higher | 8,416 (38%) | 4,394 (40%) |
Continuous variables are medians (25th to 75th percentile), except for age which is median (range)