Table 1.
Randomised controlled trials of total enteral versus total parenteral nutrition in patients with predicted severe acute pancreatitis.
| Reference | Year | Setting | Patients (n) | Allocation concealment | Reduction of infectious complications and mortality | |
|---|---|---|---|---|---|---|
| Enteral nutrition | Parenteral nutrition | |||||
| Kalfarentzos et al. [70] | 1997 | Greece | 18 | 20 | Openlabel | Significantly lower rate of pancreatic infection in the total enteral nutrition group |
| Gupta et al. [43] | 2003 | UK | 8 | 9 | Openlabel | Non-significantly lower rate of pancreatic infection in the total enteral nutrition group |
| Louie et al. [71] | 2005 | Canada | 10 | 18 | Openlabel | Non-significantly lower rate of pancreatic infection in the total enteral nutrition group |
| Eckerwall et al. [41] | 2006 | Sweden | 23 | 25 | Openlabel | No significant difference in outcomes |
| Petrov et al. [72] | 2006 | Russia | 35 | 34 | Openlabel | Significantly lower rate of pancreatic infection and mortality in the total enteral nutrition group |
| Casas et al. [73] | 2007 | Spain | 11 | 11 | Openlabel | Non-significantly lower rate of pancreatic infection in the total enteral nutrition group |
| Doley et al. [74] | 2008 | India | 25 | 25 | Openlabel | No significant difference in the outcomes |
| Wu et al. [75] | 2010 | China | 53 | 54 | Openlabel | Significantly lower rate of pancreatic infection and mortality in the total enteral nutrition group |