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. 2013 Dec 15;2013:560417. doi: 10.1155/2013/560417

Table 2.

Inhibitory effects of triterpenoid saponins on HCV replication in HCV replicon cells and in HCVcc-infected cells.

Compounds Inhibition of HCV RNA replication (EC50, μg/mL) Cytotoxicity (CC50, μg/mL)
CON1 (genotype 1b) JHF-1 (genotype 2a)
PG-extract 35 >100
PGSM 0.78 8 25
Platycodin D 0.35 3 25
Platycodin D2 1.05 12 25
Platycodin D3 2.33 27 100
Deapioplatycodin D 1.2 7 25
Deapioplatycodin D2 0.89 8 100
Platyconic acid A 2.45 22 100