. Author manuscript; available in PMC: 2014 Jan 16.

Published in final edited form as: J Med Chem. 2010 Oct 14;53(19):7146–7155. doi: 10.1021/jm101144f

Table 6.

Kinome Scan^™ profile of 26^a

Kinase	% control	Kd(nM)	Kinase	% control	Kd(nM)
mTOR	0	0.42	PIK3CA(E545K)	0.6	N.D
PIK3CA(C420R)	0.7	N.D	PIK3CA(I800L)	0	14
PIK3CA	1.3	23	MRCKA	0.65	10000

Compound 26 was profiled at a concentration of 10 μM against a diverse panel of 442 kinases by Ambit Biosciences