Figure 9.

Analysis of the genes within cluster 20 with expression enriched in germinal centre (GC) B cells. (a) The mean expression profile of all probe set intensities within cluster 29 over the 84 samples. (b) Heat map showing the mean expression intensity of each probe set in cluster 29. Each column represents the mean (log₂) probe set intensity for all samples from each source. Significant differences between groups were sought by analysis of variance. P-values for those genes that were expressed significantly (P < 0·05) by recirculating, transitional and B2 B cells at levels > 2·0-fold when compared with the other cell populations. (a, b) Samples are grouped according to cell type and are arranged in order of presentation as listed in Table S1. For each cell population mean expression levels are presented and the number of replicates is indicated in parenthesis on the x-axis. Red-boxed areas indicate the GC B-cell data sets. (c) Cartoon illustrating the putative functions of all the genes represented in cluster 20 in recirculating, transitional and B2 B cells.