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. Author manuscript; available in PMC: 2014 Jan 16.
Published in final edited form as: J Immunol. 2008 Dec 1;181(11):7562–7570. doi: 10.4049/jimmunol.181.11.7562

Figure 1.

Figure 1

SEA from S. mansoni eggs demonstrate potent Th2 adjuvanticity in vitro. DCs were pulsed with ova for 1hr prior to washing and subsequent maturation with either SEA or LPS overnight. DCs were then co-cultured with CFSE labeled naïve CD4+ purified DO.11.10 T cells. After 3 days, cells were harvested by assessed for proliferation, activation and Th2 development by intracellular IL-4 staining A. SEA-DC induces T proliferation and acquisition of a Th2 phenotype as demonstrated by increased IL-4 staining. Data are mean ± SEM from at least 3 individual experiments.