Table 2.
Formaldehyde-induced N2-OHMe-dG adducts in the nasal epithelium of rats exposed to [13CD2]-formaldehyde for 6 hr.
| exposure (ppm) | endogenous dG adduct (adducts/107 dG) | exogenous dG adducts (adducts/107 dG) |
|---|---|---|
| 0.7±0.2 | 3.62±1.33a | 0.039±0.019 |
| 2.0±0.1 | 6.09 ±3.03b | 0.19±0.08 |
| 5.8± 0.5 | 5.51 ±1.06c | 1.04 ±0.24 |
| 9.1±2.2 | 3.41 ±0.46 | 2.03 ±0.43 |
| 15.2±2.1 | 4.24 ±0.92 | 11.15±3.01 |
Adapted from Lu et al. (2011).
a
Four to six rat samples were combined for each mass spectrometry measurement; n = 3.
b
Two rat samples were combined for each mass spectrometry measurement; n = 4.
c
Rat samples were not combined for 5.8, 9.1, and 15 ppm groups; typically n = 5.