Table 1.
MicroRNA | Expression in CC | Colitis/Inherited | Reference |
---|---|---|---|
hsa-miR-15 | Up | UC | [57] |
hsa-miR-16 | Up | CD | [58] |
hsa-miR-16-2 | Up | HNPCC | [39] |
hsa-miR-18b | Hypermethylated | NS | [17] |
hsa-let-7f | Up | UC | [57] |
hsa-miR-21 | Up | CD, UC | [57] |
hsa-miR-23a | Up | UC | [57] |
hsa-miR-23b | Up | CD | [58] |
hsa-miR-24 | Up | UC | [57] |
hsa-miR-26b | Down | NS | [65] |
hsa-miR-29a | Up | IBS | [57] |
hsa-miR-30a | Up | HNPCC | [39] |
hsa-miR-31 | Up | IBD | [62] |
hsa-miR-106 | Up | CD | [58] |
hsa-miR-124a-1 | Hypermethylated | NS | [17] |
hsa-miR-124a-3 | Hypermethylated | NS | [17] |
hsa-miR-126 | Up | Active UC | [57] |
hsa-miR-143 | Down | NS | [18, 46, 47] |
hsa-miR-145 | Down | UC | [18, 46, 47] |
hsa-miR-155 | Up | CD, UC | [20, 55, 60] |
hsa-miR-191 | Up | CD | [58] |
hsa-miR-192 | Down | UC | [57] |
hsa-miR-195 | Up | UC | [57] |
hsa-miR-223 | Up | CD | [58] |
hsa-miR-275 | Up | Active UC | [58] |
hsa-miR-362-5p | Up | HNPCC | [39] |
hsa-miR-375 | Down | UC | [57] |
hsa-miR-422 | Down | UC | [57] |
hsa-miR-542-3p | Down | NS | [67] |
hsa-miR-594 | Up | CD | [58] |
hsa-mR-622 | Down | HNPCC | [39] |
hsa-miR-1238 | Down | HNPCC | [39] |
hsa-let-7f | Up | UC | [57] |
Partial list of microRNAs and expression levels in either colitis-associated or hereditary colon cancer. Abbreviations: CD, Crohn’s Disease; HNPCC, hereditary nonpolyposis colon cancer; IBS, Irritable Bowel Syndrome; NS, Not Specified; UC, Ulcerative Colitis.