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. 2013 Dec;54(6):574–578. doi: 10.3325/cmj.2013.54.574

Figure 2.

Figure 2

A novel mutation in exon 3 of the KRAS gene. The cytogenetic location of the KRAS gene is on the short (p) arm of the chromosome 12 at the position 12.1. KRAS gene comprises four exons spanning 45 kb, more precisely from base pair 25.358.179 to base pair 25.403.869 on the chromosome 12. DNA sequencing of the exone 3 and a heterozygous missense variant at the codone 179, conversing guanine to thymine (c.179G>T). The G>T conversion turns 179th triplet coding for glycine into valine (p.Gly60Val).