a, b) AR-PAM MAP coronal (left row) and sagittal images (right row) showing the degradation of a PLGA inverse opal scaffold immersed in (a) plain PBS and (b) PBS containing 0.025 wt.% lipase at 37 °C for a period of up to 6 weeks. c) Quantification of degradation using PAM volumetric data. By week 6, the scaffolds in plain PBS only degraded about 40% while the scaffolds in lipase-containing PBS had almost degraded completely. d) Quantification of the degradation in PBS in the absence and presence of lipase, respectively, using the conventional invasive mass loss assay, which showed profiles similar to what were obtained from PAM. MAP stands for “maximum amplitude projection”.