Table 1.

Patient demographics and treatment history

Category	Results
Age (years), mean ± SD, N=18	41±9
Male/female, N=19	7/12
Most common presenting symptoms,* N=15
Acral changes/change in height	10
Weight gain	5
Headaches	5
Diabetes mellitus	4
Breast discharge	4
Facial changes	4
Joint and/or muscle pain	3
Fatigue	3
Amenorrhea/irregular menstrual cycle	3
Current treatment, N=19
Somatostatin analogs	12 (63%)
GH receptor antagonist	3 (16%)
No medical therapy	4 (21%)
History of treatment since diagnosis,* N=19
One medication	7 (37%)
Two medications	7 (37%)
Three medications	1 (5%)
Four medications	2 (11%)
Surgery	18 (95%)
Radiation	3 (16%)

Note:

^*Multiple categories could be selected.

Abbreviations: SD, standard deviation; N, number; GH, growth hormone.