Table 1. Summary of the main characteristics of GIMME [8], MBA [10], iMAT [35], mCADRE [26], INIT [13], and fastcore (this paper) reconstruction algorithms.

	GIMME	MBA	iMAT	mCADRE	INIT	FASTCORE
Optimization	LP	MILP	MILP	MILP	MILP	LP
Computational cost	low	high	high	high	high	low
Function required	yes	no	no	yes	yes	no
Omics required	yes	optional	yes	yes	yes	no
Code available	yes	yes	yes	yes	no	yes