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. 2014 Jan 16;9(1):e84052. doi: 10.1371/journal.pone.0084052

Table 2. Clinical parameters of baseline and follow-up according to the change of body fat percentage.

Baseline study Follow-up study
Changes of body fat percentage Changes of body fat percentage
1st 2nd 3rd P 1st 2nd 3rd P
Age (yr) 71.3±6.9 70.6±6.0 71.6±6.4 0.429
Sex (%) 72 (55.4) 69 (53.1) 58 (44.6) 0.188
SBP (mmHg) 133.2±16.6 132.5±15.3 131.1±18.3 0.611 125.3±16.7 123±15.9 125.6±16.0 0.379
BMI (kg/m2) 24.2±2.9 24.4±3.1 24.2±3.4 0.829 23.0±2.8 24.2±3.2 25.1±3.4 <0.001
WC (cm) 85.5±8.8 85.6±8.9 87.9±9.7 0.085 84.4±7.9 86.9±7.7 89.6±8.7 <0.001
WHR 0.91±0.08 0.91±0.09 0.93±0.09 0.247 0.90±0.6 0.90±0.05 0.92±0.05 0.017
eGFR(ml/min/1.73 cm2) 75.4±13.9 75.5±15.6 75.5±16.2 0.996 75.2±13.3 73.6±15.7 70.9±16.6 0.075
Proteinuria(%) 10 (7.8) 6 (4.7) 8(6.2) 0.576 6(4.7) 7 (5.5) 8(6.2) 0.867
WBC(×103/µL) 6.1±1.7 6.4±1.6 6.3±1.6 0.183 5.7±1.6 6.1±1.56 6.3±1.7 0.017
ESR (mm/hr) 19.1±13.6 16.5±10.4 18.6±13.4 0.194 12.7±12.1 11.2±9.7 16.1±14.4 0.006
HDL (mg/dL) 63.6±15.4 59.4±14.3 60.0±15.1 0.049 55.5±14.2 52.0±12.2 51.8±13.1 0.043
TG (mg/dL) 124.2±67.3 153.0±105.1 138.2±103.1 0.047 113.7±56.3 141.3±87.0 139.5±84.2 0.007
HbA1c (%) 6.1±0.9 6.1±0.9 6.1±0.8 0.971 6.02±0.70 6.18±0.79 6.25±0.89 0.087
Albumin (g/dL) 4.1±0.2 4.2±0.2 4.1±0.2 0.124 4.4±0.3 4.4±0.2 4.4±0.3 0.549
HTN (%) 87 (66.9) 93 (71.5) 95 (73.1) 0.527
DM (%) 28 (21.5) 36 (27.7) 34 (26.2) 0.492
CVA (%) 16 (12.3) 14 (10.8) 12 (9.2) 0.625
Exercise (%) 100 (76.9) 86 (66.2) 74 (56.9) 0.003

Measurements taken at follow-up showed marked differences in body composition, inflammation level, and lipid profile amongst tertiles of body fat change, despite no differences at baseline.

Abbreviations: BMI, body mass index; WC, waist circumference; WHR, waist-to-hip ratio; eGFR, estimated glomerular filtration rate; WBC, white blood cell, ESR, erythrocyte sedimentation rate; HDL, high density lipoprotein cholesterol, TG, triglyceride; HTN, hypertension; DM, diabetes mellitus, CVA, cerebrovascular accident.