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. 2014 Jan 16;10(1):e1003847. doi: 10.1371/journal.ppat.1003847

Table 3. Transcription and translation coordinates, and function of primary ORFs without determined time of expression.

Gene Str TSS-PolyA Start-Stop Ann Variant Timing Function Ref
ORF2 N/A 18534–17902 P N/A dihydrofolate reductase [137], [138]
ORF7 + N/A 6609–8696 M N/A virion protein [136]
ORF48 N/A 71197–69989 P N/A N/A
ORF49 N/A-71432 72354–71446 P N/A Activates JNK/p38 [139]
ORF63 + N/A 101027–103813 P N/A NLR homolog [140]
ORF64 + N/A 103819–111726 P N/A Deubiquitinase [139]
ORFK15 N/A N/A N/A Internal N/A LMP1/2 [141]

Timing of expression could not be determined for these genes due to overlapping transcripts or low sequencing coverage. Str: Strand; TSS: transcription start site; N/A, not determined in silico or by manual annotation; Ann: Annotation; P: predicted; M: manual annotation; Internal: ORF with internal ORFs.