Table 3. Transcription and translation coordinates, and function of primary ORFs without determined time of expression.
Gene | Str | TSS-PolyA | Start-Stop | Ann | Variant | Timing | Function | Ref |
ORF2 | − | N/A | 18534–17902 | P | N/A | dihydrofolate reductase | [137], [138] | |
ORF7 | + | N/A | 6609–8696 | M | N/A | virion protein | [136] | |
ORF48 | − | N/A | 71197–69989 | P | N/A | N/A | ||
ORF49 | − | N/A-71432 | 72354–71446 | P | N/A | Activates JNK/p38 | [139] | |
ORF63 | + | N/A | 101027–103813 | P | N/A | NLR homolog | [140] | |
ORF64 | + | N/A | 103819–111726 | P | N/A | Deubiquitinase | [139] | |
ORFK15 | − | N/A | N/A | N/A | Internal | N/A | LMP1/2 | [141] |
Timing of expression could not be determined for these genes due to overlapping transcripts or low sequencing coverage. Str: Strand; TSS: transcription start site; N/A, not determined in silico or by manual annotation; Ann: Annotation; P: predicted; M: manual annotation; Internal: ORF with internal ORFs.