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RNAi was performed in cultured schistosomulae as described in Fig. 6 except that motility was measured both in the absence and presence of added serotonin (+5HT) at 10−4 M. Data are the means and SEM of 40 animals and 2–3 transfections per treatment. **, significantly different from basal activity (measured in the absence of serotonin) at p<0.001. ns, not significant at p<0.05.
